5495 results for:

1. RMgm-1

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_0514900; Gene model (P.falciparum): PF3D7_1030900; Gene product: ookinete surface protein P28 (Pbs21; P28)
   Phenotype	Fertilization and ookinete; Oocyst;

   
   
2. RMgm-2

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_0515000; Gene model (P.falciparum): PF3D7_1031000; Gene product: ookinete surface protein P25 (Pbs25; P25)
   Phenotype	Fertilization and ookinete; Oocyst;

   
   
3. RMgm-3

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_0514900; Gene model (P.falciparum): PF3D7_1030900; Gene product: ookinete surface protein P28 (Pbs21; P28)
   Disrupted	Gene model (rodent): PBANKA_0515000; Gene model (P.falciparum): PF3D7_1031000; Gene product: ookinete surface protein P25 (Pbs25; P25)
   Phenotype	Fertilization and ookinete; Oocyst;

   
   
4. RMgm-4

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_0522700; Gene model (P.falciparum): PF3D7_0422300; Gene product: alpha tubulin 2
   Phenotype	No phenotype has been described

   
   
5. RMgm-5

   Malaria parasite	P. berghei
   Genotype
   Transgene	Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit))
   Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

   
   
6. RMgm-7

   Malaria parasite	P. berghei
   Genotype
   Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
   Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

   
   
7. RMgm-9

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP)
   Phenotype	Oocyst; Sporozoite; Liver stage;

   
   
8. RMgm-10

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 (AMA1)
   Phenotype	No phenotype has been described

   
   
9. RMgm-11

   Malaria parasite	P. berghei
   Genotype
   Transgene	Transgene Plasmodium: Gene model: PF3D7_1133400; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 (AMA1) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 (AMA1; pb66) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
   Phenotype	Asexual bloodstage;

   
   
10. RMgm-12

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4)
    Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

    
    
11. RMgm-13

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: GFP-aequorin (Ca2+ sensor protein). Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-or d-type unit))
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

    
    
12. RMgm-15

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1359600; Gene model (P.falciparum): PF3D7_1346700; Gene product: 6-cysteine protein | transmission blocking target antigen precursor (P48/45)
    Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

    
    
13. RMgm-16

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0524800; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein small exported protein (SEP1; ETRAMP; Pbsep1)
    Phenotype	No phenotype has been described

    
    
14. RMgm-18

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0524800; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein small exported protein (SEP1; ETRAMP; Pbsep1)
    Phenotype	No phenotype has been described

    
    
15. RMgm-21

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0521221; Gene model (P.falciparum): Not available; Gene product: 18S ribosomal RNA (small subunit (ssu) of the c-type ribosomal rna gene unit)
    Phenotype	Oocyst;

    
    
16. RMgm-22

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0521261; Gene model (P.falciparum): Not available; Gene product: 28S ribosomal RNA (large subunit (lsu) of the c-type ribosomal rna gene unit)
    Phenotype	Oocyst;

    
    
17. RMgm-23

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0622921; Gene model (P.falciparum): Not available; Gene product: 18S ribosomal RNA (small subunit (ssu) of the d-type ribosomal rna gene unit)
    Phenotype	Oocyst; Sporozoite;

    
    
18. RMgm-24

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0622961; Gene model (P.falciparum): Not available; Gene product: 28S ribosomal RNA (large subunit (lsu) of the d-type ribosomal rna gene unit)
    Phenotype	Oocyst; Sporozoite;

    
    
19. RMgm-25

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0622921; Gene model (P.falciparum): Not available; Gene product: 18S ribosomal RNA (small subunit (ssu) of the d-type ribosomal rna gene unit)
    Phenotype	Oocyst; Sporozoite;

    
    
20. RMgm-26

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1444000; Gene model (P.falciparum): PF3D7_1229400; Gene product: macrophage migration inhibitory factor (MIF)
    Phenotype	Asexual bloodstage;

    
    
21. RMgm-27

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_1444000; Gene model (P.falciparum): PF3D7_1229400; Gene product: macrophage migration inhibitory factor (MIF) Name tag: EGFP
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

    
    
22. RMgm-28

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-65) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit))
    Phenotype	Asexual bloodstage; Gametocyte/Gamete;

    
    
23. RMgm-29

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Oocyst; Sporozoite; Liver stage;

    
    
24. RMgm-30

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (d-type unit))
    Phenotype	Asexual bloodstage;

    
    
25. RMgm-31

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_1444000; Gene model (P.falciparum): PF3D7_1229400; Gene product: macrophage migration inhibitory factor (MIF) Name tag: c-myc
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Sporozoite; Liver stage;

    
    
26. RMgm-32

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Phenotype	Asexual bloodstage; Oocyst; Sporozoite; Liver stage;

    
    
27. RMgm-33

    Malaria parasite	P. chabaudi
    Genotype
    Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (ssu-rrna locus (contig 827))
    Phenotype	Asexual bloodstage;

    
    
28. RMgm-34

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0209100; Gene model (P.falciparum): PF3D7_0104000; Gene product: thrombospondin-related sporozoite protein | sporozoite stage TSP1 domain protein (thrombospondin related sporozoite protein; TRSP; Sporozoite stage TSP1 domain protein, S21)
    Phenotype	Sporozoite; Liver stage;

    
    
29. RMgm-35

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0501200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 | protein of early gametocyte 4 (UIS4; ETRAMP10.3)
    Phenotype	Liver stage;

    
    
30. RMgm-36

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1400800; Gene model (P.falciparum): PF3D7_1302200; Gene product: early transcribed membrane protein 13 (UIS3; up-regulated in infective sporozoites; ETRAMP13)
    Phenotype	Liver stage;

    
    
31. RMgm-37

    Malaria parasite	P. yoelii
    Genotype
    Disrupted	Gene model (rodent): PY17X_1402400; Gene model (P.falciparum): PF3D7_1302200; Gene product: early transcribed membrane protein 13 (UIS3; up-regulated in infective sporozoites; ETRAMP13)
    Phenotype	Liver stage;

    
    
32. RMgm-38

    Malaria parasite	P. yoelii
    Genotype
    Disrupted	Gene model (rodent): PY17X_0502200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 | protein of early gametocyte 4 (UIS4, up-regulated in infective sporozoites, ETRAMP10.3)
    Phenotype	Liver stage;

    
    
33. RMgm-39

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1400800; Gene model (P.falciparum): PF3D7_1302200; Gene product: early transcribed membrane protein 13 (UIS3; up-regulated in infective sporozoites; ETRAMP13)
    Disrupted	Gene model (rodent): PBANKA_0501200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 | protein of early gametocyte 4 (UIS4; ETRAMP10.3)
    Phenotype	Liver stage;

    
    
34. RMgm-40

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1002200; Gene model (P.falciparum): PF3D7_0404500; Gene product: 6-cysteine protein (P36p; Pb36p; P52)
    Phenotype	Liver stage;

    
    
35. RMgm-41

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1002200; Gene model (P.falciparum): PF3D7_0404500; Gene product: 6-cysteine protein (P36p; Pb36p; P52)
    Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit))
    Phenotype	Liver stage;

    
    
36. RMgm-42

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1002200; Gene model (P.falciparum): PF3D7_0404500; Gene product: 6-cysteine protein (P36p; Pb36p; P52)
    Disrupted	Gene model (rodent): PBANKA_1002100; Gene model (P.falciparum): PF3D7_0404400; Gene product: 6-cysteine protein (P36)
    Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Phenotype	Liver stage;

    
    
37. RMgm-43

    Malaria parasite	P. yoelii
    Genotype
    Disrupted	Gene model (rodent): PY17X_1003600; Gene model (P.falciparum): PF3D7_0404500; Gene product: 6-cysteine protein (P36p; Pb36p; P52)
    Disrupted	Gene model (rodent): PY17X_1003500; Gene model (P.falciparum): PF3D7_0404400; Gene product: 6-cysteine protein (P36)
    Phenotype	Liver stage;

    
    
38. RMgm-44

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1002200; Gene model (P.falciparum): PF3D7_0404500; Gene product: 6-cysteine protein (P36p; Pb36p; P52)
    Phenotype	Liver stage;

    
    
39. RMgm-45

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1002100; Gene model (P.falciparum): PF3D7_0404400; Gene product: 6-cysteine protein (P36)
    Phenotype	Liver stage;

    
    
40. RMgm-46

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1432300; Gene model (P.falciparum): PF3D7_1216600; Gene product: cell traversal protein for ookinetes and sporozoites (CelTOS; cell traversal protein for ookinetes and sporozoites)
    Phenotype	Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

    
    
41. RMgm-47

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP)
    Phenotype	Sporozoite; Liver stage;

    
    
42. RMgm-48

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation of the A-domain
    Phenotype	Sporozoite; Liver stage;

    
    
43. RMgm-49

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation of the A-domain
    Phenotype	Sporozoite; Liver stage;

    
    
44. RMgm-50

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation of the TSR-domain (the distal tryptophan in the WSXW sequence was substituted by alanine)
    Phenotype	Sporozoite; Liver stage;

    
    
45. RMgm-51

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation of the TSR-domain (basic residues in the C-terminal cluster changed to alanine residues).
    Phenotype	Sporozoite; Liver stage;

    
    
46. RMgm-52

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutations in both the A- and TSR-domain
    Phenotype	Sporozoite; Liver stage;

    
    
47. RMgm-53

    Malaria parasite	P. yoelii
    Genotype
    Disrupted	Gene model (rodent): PY17X_1354800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP)
    Phenotype	Sporozoite; Liver stage;

    
    
48. RMgm-54

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation in the cytoplasmic tail (abrogation of the tyrosine motif)
    Phenotype	Sporozoite; Liver stage;

    
    
49. RMgm-55

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation in the cytoplasmic tail (lacking the 14 carboxy-terminal residues)
    Phenotype	Sporozoite; Liver stage;

    
    
50. RMgm-56

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation in the cytoplasmic tail (lacking the 37 carboxy-terminal residues)
    Phenotype	Sporozoite; Liver stage;

    
    
51. RMgm-57

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The cytoplasmic tail domain (CTD) of TRAP replaced with the CTD of T. gondii MIC2
    Phenotype	No phenotype has been described

    
    
52. RMgm-58

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The endogenous P. berghei gene replaced with the ortholog of P. falciparum
    Phenotype	Sporozoite; Liver stage;

    
    
53. RMgm-59

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0616700; Gene model (P.falciparum): PF3D7_0719200; Gene product: NIMA related kinase 4 (serine/threonine protein kinase, Pfnek-4)
    Phenotype	Fertilization and ookinete;

    
    
54. RMgm-60

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0616700; Gene model (P.falciparum): PF3D7_0719200; Gene product: NIMA related kinase 4 (serine/threonine protein kinase, Pfnek-4)
    Phenotype	Fertilization and ookinete;

    
    
55. RMgm-62

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0933700; Gene model (P.falciparum): PF3D7_1113900; Gene product: mitogen-activated protein kinase 2 (MAP2; MAP-2; MAPK2)
    Phenotype	Fertilization and ookinete;

    
    
56. RMgm-63

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0933700; Gene model (P.falciparum): PF3D7_1113900; Gene product: mitogen-activated protein kinase 2 (MAP2; MAP-2; MAPK2)
    Phenotype	Fertilization and ookinete;

    
    
57. RMgm-64

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_0524200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein; small exported protein (SEP2; ETRAMP4; Pbsep2)
    Phenotype	No phenotype has been described

    
    
58. RMgm-65

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_0501100; Gene model (P.falciparum): Not available; Gene product: small exported protein early transcribed membrane protein (SEP3; SEP-ter; ETRAMP; PbSep3)
    Phenotype	No phenotype has been described

    
    
59. RMgm-66

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0933700; Gene model (P.falciparum): PF3D7_1113900; Gene product: mitogen-activated protein kinase 2 (MAP2; MAP-2; MAPK2)
    Phenotype	Fertilization and ookinete;

    
    
60. RMgm-68

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: Region II plus (substituted with alanines)
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
61. RMgm-69

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The endogenous P. berghei gene replaced with the ortholog of P. falciparum
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
62. RMgm-70

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The endogenous P. berghei gene replaced with the ortholog of P. falciparum, lacking region I
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
63. RMgm-71

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The endogenous P. berghei gene replaced with the ortholog of P. falciparum, lacking region II
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
64. RMgm-72

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: truncation of the 3'UTR of the gene
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
65. RMgm-73

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: Mutations of the C-terminal glycosylphosphatidylinositol (GPI)-anchor addition sequence
    Phenotype	Oocyst; Sporozoite;

    
    
66. RMgm-74

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The endogenous P. berghei gene replaced with the homolog of P. gallinaceum
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
67. RMgm-75

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The endogenous P. berghei gene replaced with the ortholog of P. yoelii
    Phenotype	No phenotype has been described

    
    
68. RMgm-76

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The repeat region of the endogenous gene is exchanged with the P. falciparum repeat region
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
69. RMgm-77

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) 3'UTR: Gene model: PBANKA_0403200; Gene product: circumsporozoite (CS) protein (CSP) Insertion locus: Gene model: PBANKA_0403200; Gene product: circumsporozoite (CS) protein (CSP)
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
70. RMgm-78

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: drFP583/DsRed/RFP, RedStar Promoter: Gene model: PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR/TS) Insertion locus: Gene model: Not available; Gene product: Not available
    Phenotype	Sporozoite;

    
    
71. RMgm-79

    Malaria parasite	P. yoelii
    Genotype
    Transgene	Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR/TS) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (P. yoelii))
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Oocyst; Sporozoite; Liver stage;

    
    
72. RMgm-80

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_0509500; Gene model (P.falciparum): PF3D7_1025300; Gene product: conserved Plasmodium protein, unknown function (PSOP21, putative secreted ookinete protein 21)
    Phenotype	No phenotype has been described

    
    
73. RMgm-81

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_1338900; Gene model (P.falciparum): PF3D7_1323700; Gene product: glideosome associated protein with multiple membrane spans 1 (PSOP23, putative secreted ookinete protein 23)
    Phenotype	No phenotype has been described

    
    
74. RMgm-82

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_0204800; Gene model (P.falciparum): PF3D7_0108700; Gene product: secreted ookinete protein, putative (PSOP24, putative secreted ookinete protein 24)
    Phenotype	No phenotype has been described

    
    
75. RMgm-83

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_1434400; Gene model (P.falciparum): PF3D7_1218800; Gene product: secreted ookinete protein, putative (PSOP17, putative secreted ookinete protein 17)
    Phenotype	No phenotype has been described

    
    
76. RMgm-84

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_1222500; Gene model (P.falciparum): PF3D7_0808200; Gene product: plasmepsin X (plasmepsin X; aspartyl protease)
    Phenotype	No phenotype has been described

    
    
77. RMgm-86

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: drFP583/DsRed/RFP, RedStar Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR/TS) Insertion locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

    
    
78. RMgm-87

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1228900; Gene model (P.falciparum): PF3D7_0801300; Gene product: von Willebrand factor A domain-related protein (WARP)
    Phenotype	No phenotype has been described

    
    
79. RMgm-88

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0619200; Gene model (P.falciparum): PF3D7_0721700; Gene product: secreted ookinete protein, putative (PSOP1, putative secreted ookinete protein 1)
    Phenotype	No phenotype has been described

    
    
80. RMgm-89

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1113400; Gene model (P.falciparum): PF3D7_0513700; Gene product: secreted ookinete protein, putative | 6-cysteine protein (PSOP12, putative secreted ookinete protein 12)
    Phenotype	No phenotype has been described

    
    
81. RMgm-90

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0209200; Gene model (P.falciparum): PF3D7_0103900; Gene product: parasite-infected erythrocyte surface protein (PIESP15, parasite infected erythrocyte surface protein 15)
    Phenotype	No phenotype has been described

    
    
82. RMgm-91

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1421700; Gene model (P.falciparum): PF3D7_0715400; Gene product: secreted ookinete protein, putative (PSOP20, putative secreted ookinete protein 20)
    Phenotype	No phenotype has been described

    
    
83. RMgm-93

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_1129000; Gene model (P.falciparum): PF3D7_0630200; Gene product: secreted ookinete protein, putative (PSOP6, putative secreted ookinete protein 6)
    Phenotype	No phenotype has been described

    
    
84. RMgm-95

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0701900; Gene model (P.falciparum): PF3D7_0828800; Gene product: GPI-anchored micronemal antigen (PSOP9; putative secreted ookinete protein 9; GAMA)
    Phenotype	Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

    
    
85. RMgm-96

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1353400; Gene model (P.falciparum): PF3D7_1340000; Gene product: secreted ookinete protein, putative (PSOP7; putative secreted ookinete protein 7)
    Phenotype	Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

    
    
86. RMgm-97

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0409700; Gene model (P.falciparum): PF3D7_0311700; Gene product: plasmepsin VI (aspartyl protease)
    Phenotype	Oocyst; Sporozoite;

    
    
87. RMgm-98

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1315300; Gene model (P.falciparum): PF3D7_1451600; Gene product: LCCL domain-containing protein (LAP5; FNPA, PbFNPA)
    Phenotype	Oocyst; Sporozoite;

    
    
88. RMgm-99

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1143700; Gene model (P.falciparum): PF3D7_1367800; Gene product: secreted ookinete protein, putative (PSOP2, putative secreted ookinete protein 2)
    Phenotype	Fertilization and ookinete; Oocyst; Sporozoite;

    
    
89. RMgm-100

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1217700; Gene model (P.falciparum): PF3D7_0320800; Gene product: ATP-dependent RNA helicase DDX6 (DOZI, protein development of zygote inhibited)
    Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

    
    
90. RMgm-101

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1233600; Gene model (P.falciparum): PF3D7_0518800; Gene product: secreted ookinete protein, putative (PSOP13, putative secreted ookinete protein 13)
    Phenotype	Oocyst; Sporozoite;

    
    
91. RMgm-102

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0304700; Gene model (P.falciparum): PF3D7_0207300; Gene product: serine repeat antigen 8 (ECP1, egress cysteine protease 1; PbSERA5)
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
92. RMgm-103

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_1327100; Gene model (P.falciparum): PF3D7_1463900; Gene product: EF-hand calcium-binding domain-containing protein, putative
    Phenotype	No phenotype has been described

    
    
93. RMgm-104

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_0209000; Gene model (P.falciparum): PF3D7_0104100; Gene product: conserved Plasmodium membrane protein, unknown function
    Phenotype	No phenotype has been described

    
    
94. RMgm-105

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0934600; Gene model (P.falciparum): PF3D7_1113000; Gene product: conserved Plasmodium protein, unknown function
    Phenotype	No phenotype has been described

    
    
95. RMgm-106

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1034500; Gene model (P.falciparum): PF3D7_1407700; Gene product: conserved Plasmodium protein, unknown function
    Phenotype	No phenotype has been described

    
    
96. RMgm-107

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1123700; Gene model (P.falciparum): PF3D7_0624800; Gene product: conserved Plasmodium protein, unknown function
    Phenotype	No phenotype has been described

    
    
97. RMgm-108

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1309600; Gene model (P.falciparum): PF3D7_1445800; Gene product: conserved Plasmodium membrane protein, unknown function
    Phenotype	Oocyst; Sporozoite;

    
    
98. RMgm-109

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1006200; Gene model (P.falciparum): PF3D7_0408600; Gene product: sporozoite invasion-associated protein 1 (Sporozoite Invasion-Associated Protein-1; SIAP-1; SIAP-1/ag17/S5)
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
99. RMgm-110

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0712200; Gene model (P.falciparum): PF3D7_0818600; Gene product: BEM46-like protein, putative
    Phenotype	Oocyst; Sporozoite; Liver stage;

    
    
100. RMgm-111

     Malaria parasite	P. berghei
     Genotype
     Tagged	Gene model (rodent): PBANKA_1143700; Gene model (P.falciparum): PF3D7_1367800; Gene product: secreted ookinete protein, putative (PSOP2, putative Secreted Ookinete Protein 2) Name tag: c-myc
     Phenotype	Fertilization and ookinete;