Search database by RMgm ID
RMgm-628
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Name tag: mCherry |
Phenotype |
Asexual bloodstage;
Sporozoite; |
RMgm-685
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Details mutation: The mutant contains a mutated ron4 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of ron4 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Insertion locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts; pbdhfr/ts) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-686
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) |
Phenotype | No phenotype has been described |
RMgm-1034
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_0934000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Name tag: mCherry |
Phenotype |
Asexual bloodstage;
Sporozoite; Liver stage; |
RMgm-1348
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1007700; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 | sporozoite micronemal protein essential for cell traversal (PLP1; PPLP1, SPECT2) |
Tagged | Gene model (rodent): PY17X_0934000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Name tag: mCherry |
Phenotype |
Sporozoite; Liver stage; |
RMgm-2636
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 |
Phenotype | No phenotype has been described |
RMgm-4691
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Name tag: c-myc |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Sporozoite; |
RMgm-4713
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Name tag: c-myc |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Oocyst;
Sporozoite; |
RMgm-4866
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Details mutation: 'promoter-swap' mutant; the RON4 promoter replaced by the promoter of PBANKA_1443300 (msp9) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-5139
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0808100; Gene model (P.falciparum): PF3D7_0317100; Gene product: 6-cysteine protein (B9) |
Tagged | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Name tag: mCherry |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0808100; Gene product: 6-cysteine protein (B9) |
Phenotype |
Asexual bloodstage;
Sporozoite; Liver stage; |
RMgm-5152
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Details mutation: The mutant contains a mutated ron4 gene with two LoxN sites (up- and downstream of the gene) |
Transgene |
Transgene not Plasmodium: DiCre Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): heat shock protein 70; Gene product: HSP70 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-5392
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Name tag: mCherry |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
Phenotype |
Sporozoite; Liver stage; |