RMgmDB - Rodent Malaria genetically modified Parasites

Search for genetically modified parasite lines by:

Gene ID (single gene): P. falciparum or rodent parasite  



       
 
 
 
 
  

Gene ID (multiple genes): P. falciparum or rodent parasite  

Each gene IDs must be placed on a separate line.
Do not use spaces, commas, semi-colons, etc.

The output from this search will include the following fields (in CSV format):
Gene ID (rodent and P. falciparum), RMgm ID, (un)successful modification, type of genetic modification, life cycle stages with phenotype.


         

For example ama1, ookinete, gamete, GFP

First select the phenotype:

Then select the type of modification:

         

Search database by RMgm ID



5585 results for:

  1. RMgm-5459
    Malaria parasiteP. berghei
    Genotype
    Genetic modification not successful
    DisruptedGene model (rodent): PBANKA_0515350; Gene model (P.falciparum): PF3D7_1031400; Gene product: OTU-like cysteine protease (Otu)
    DisruptedGene model (rodent): PBANKA_1025400; Gene model (P.falciparum): PF3D7_1417300; Gene product: cysteine protease ATG4, putative (ATG4)
    PhenotypeNo phenotype has been described
  2. RMgm-5460
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0317500; Gene model (P.falciparum): Not available; Gene product: erythrocyte membrane associated protein 2, putative (EMAP2)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  3. RMgm-5461
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0312300; Gene model (P.falciparum): PF3D7_0215300; Gene product: acyl-CoA synthetase (ACS8)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  4. RMgm-5462
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0840300; Gene model (P.falciparum): Not available; Gene product: acyl-erythrocyte membrane associated protein 1CoA synthetase (EMAP1)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  5. RMgm-5463
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0418800; Gene model (P.falciparum): PF3D7_0905400; Gene product: high molecular weight rhoptry protein 3 (RhopH3)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  6. RMgm-5464
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1371300; Gene model (P.falciparum): Not available; Gene product: exported protein IBIS1 (IBIS1)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  7. RMgm-5465
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0203000; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein (ETRAMP)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  8. RMgm-5466
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1232500; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein (PHIST) unknown function (PHISTc)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  9. RMgm-5467
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0839900; Gene model (P.falciparum): Not available; Gene product: conserved rodent malaria protein unknown function
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  10. RMgm-5468
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1331400; Gene model (P.falciparum): Not available; Gene product: fam-1 protein
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  11. RMgm-5469
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1400400; Gene model (P.falciparum): Not available; Gene product: PIR protein
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  12. RMgm-5470
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0701100; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein unknown function
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  13. RMgm-5471
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0216200; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein unknown function
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  14. RMgm-5472
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0626000; Gene model (P.falciparum): Not available; Gene product: tryptophan-rich protein
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  15. RMgm-5473
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0621900; Gene model (P.falciparum): Not available; Gene product: secreted ookinete protein (PSOP1)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  16. RMgm-5474
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0822300; Gene model (P.falciparum): PF3D7_0918000; Gene product: glideosome-associated protein 50 (GAP50)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  17. RMgm-5475
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0936300; Gene model (P.falciparum): PF3D7_1113300; Gene product: UDP-galactose transporter (UGT)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  18. RMgm-5476
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1109000; Gene model (P.falciparum): PF3D7_0508300; Gene product: triose phosphate transporter (TPT)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  19. RMgm-5477
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0920800; Gene model (P.falciparum): PF3D7_1129100; Gene product: parasitophorous vacuolar protein 1 r (PV1)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  20. RMgm-5478
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0518100; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein (ETRAMP)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  21. RMgm-5479
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0701400; Gene model (P.falciparum): Not available; Gene product: CRA domain-containing protein
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  22. RMgm-5480
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1102500; Gene model (P.falciparum): PF3D7_0501600; Gene product: rhoptry-associated protein 2/3 (RAP2/3)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  23. RMgm-5481
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0809600; Gene model (P.falciparum): PF3D7_0318900; Gene product: conserved protein unknown function
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  24. RMgm-5482
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1422000; Gene model (P.falciparum): PF3D7_0713700; Gene product: conserved Plasmodium protein unknown function
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  25. RMgm-5483
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1308700; Gene model (P.falciparum): PF3D7_1441000; Gene product: cytoplasmic tRNA 2-thiolation protein 2 (NCS2)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  26. RMgm-5484
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0836300; Gene model (P.falciparum): PF3D7_0932100; Gene product: protein MAM3 (NCS2)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  27. RMgm-5485
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0514900; Gene model (P.falciparum): PF3D7_1029800; Gene product: RAP protein (NCS2)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  28. RMgm-5486
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1243200; Gene model (P.falciparum): PF3D7_0525200; Gene product: structural maintenance of chromosomes protein 6 (SMC6)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  29. RMgm-5487
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1408300; Gene model (P.falciparum): PF3D7_1308100; Gene product: CCAAT-binding transcription factor
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  30. RMgm-5488
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1243800; Gene model (P.falciparum): PF3D7_0525800; Gene product: inner membrane complex protein 1g (IMC1g)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  31. RMgm-5489
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1309700; Gene model (P.falciparum): PF3D7_1442000; Gene product: ADP-ribosylation factor
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  32. RMgm-5490
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1039400; Gene model (P.falciparum): PF3D7_1405200; Gene product: trafficking protein particle complex subunit 1 (BET5)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  33. RMgm-5491
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0519600; Gene model (P.falciparum): PF3D7_1034700; Gene product: ADP-ribosylation factor
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  34. RMgm-5492
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0622600; Gene model (P.falciparum): PF3D7_0722400; Gene product: Obg-like ATPase 1 (OLA1)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  35. RMgm-5493
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0826700; Gene model (P.falciparum): PF3D7_0922500; Gene product: phosphoglycerate kinase (PGK)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  36. RMgm-5494
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0839000; Gene model (P.falciparum): PF3D7_0932000; Gene product: conserved Plasmodium protein unknown function
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  37. RMgm-5495
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0839000; Gene model (P.falciparum): PF3D7_0934800; Gene product: cAMP-dependent protein kinase catalytic subunit (PKAc)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  38. RMgm-5496
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1033100; Gene model (P.falciparum): PF3D7_1411800; Gene product: conserved Plasmodium protein unknown function
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  39. RMgm-5497
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1345100; Gene model (P.falciparum): PF3D7_1325200; Gene product: lactate dehydrogenase
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  40. RMgm-5498
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1404800; Gene model (P.falciparum): PF3D7_1304700; Gene product: cyclin
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  41. RMgm-5499
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0523900; Gene model (P.falciparum): PF3D7_0422100; Gene product: transmembrane emp24 domain-containing protein
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  42. RMgm-5500
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0617500; Gene model (P.falciparum): PF3D7_0717100; Gene product: conserved Plasmodium protein unknown function
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  43. RMgm-5501
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0933500; Gene model (P.falciparum): PF3D7_1116500; Gene product: folate transporter 2 (FT2)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  44. RMgm-5502
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1365400; Gene model (P.falciparum): PF3D7_1346800; Gene product: 6-cysteine protein (P47)
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  45. RMgm-5503
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1222400; Gene model (P.falciparum): PF3D7_0708700; Gene product: Cg8 protein
    Name tag: EGFP
    Phenotype Asexual bloodstage;

  46. RMgm-5504
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0701000; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein, unknown function
    Name tag: HA
    Phenotype Asexual bloodstage;

  47. RMgm-5505
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0701100; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein, unknown function
    Name tag: HA
    Phenotype Asexual bloodstage;

  48. RMgm-5506
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1102300; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein, unknown function
    Name tag: HA
    Phenotype Asexual bloodstage;

  49. RMgm-5507
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1001800; Gene model (P.falciparum): PF3D7_0803600; Gene product: GRAM domain-containing protein, putative
    Name tag: HA
    Phenotype Asexual bloodstage;

  50. RMgm-5508
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0526100; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein, unknown function
    Name tag: HA
    Phenotype Asexual bloodstage;

  51. RMgm-5509
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1210300; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein, unknown function
    Name tag: HA
    Phenotype Asexual bloodstage;

  52. RMgm-5510
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0802800; Gene model (P.falciparum): PF3D7_0803600; Gene product: GRAM domain-containing protein, putative
    Name tag: HA
    Phenotype Asexual bloodstage;

  53. RMgm-5511
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0839600; Gene model (P.falciparum): Not available; Gene product: conserved Plasmodium protein, unknown function
    Name tag: HA
    Phenotype Asexual bloodstage;

  54. RMgm-5512
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1321800; Gene model (P.falciparum): PF3D7_1454300; Gene product: SNF1-related serine/threonine protein kinase KIN
    Name tag: HA
    Phenotype Asexual bloodstage;

  55. RMgm-5513
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0701300; Gene model (P.falciparum): Not available; Gene product: sporozoite and liver stage tryptophan-rich protein, putative
    Name tag: HA
    Phenotype Asexual bloodstage;

  56. RMgm-5514
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_0920100; Gene model (P.falciparum): PF3D7_1128100; Gene product: prefoldin subunit 5, putative (PbPCS5)
    Transgene
    		 Transgene not Plasmodium: mcherry
    Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
    3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70)
    Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Transgene
    		 Transgene not Plasmodium: Luciferase
    Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
    3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
    Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p; 230p)
    Phenotype Oocyst; Sporozoite;

  57. RMgm-5515
    Malaria parasiteP. yoelii
    Genotype
    Genetic modification not successful
    DisruptedGene model (rodent): PY17X_1241800; Gene model (P.falciparum): PF3D7_0523800; Gene product: food vacuole resident transporter 1 (FVRT1, PyDMT1 (Divalent metal transporter 1))
    PhenotypeNo phenotype has been described
  58. RMgm-5516
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1241800; Gene model (P.falciparum): PF3D7_0523800; Gene product: food vacuole resident transporter 1 (FVRT1, PyDMT1 (Divalent metal transporter 1))
    Name tag: HA
    Phenotype Asexual bloodstage;

  59. RMgm-5517
    Malaria parasiteP. yoelii
    Genotype
    MutatedGene model (rodent): PY17X_1241800; Gene model (P.falciparum): PF3D7_0523800; Gene product: food vacuole resident transporter 1 (FVRT1, PyDMT1 (Divalent metal transporter 1))
    Details mutation: The 5' UTR of the dmt1 gene is truncated.
    Phenotype Asexual bloodstage;

  60. RMgm-5518
    Malaria parasiteP. berghei
    Genotype
    MutatedGene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP)
    Details mutation: The P. berghei csp gene replaced by P. falciparum csp
    Transgene
    		 Transgene not Plasmodium: GFP
    Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
    3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
    Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p; 230p)
    Phenotype Oocyst; Sporozoite;

  61. RMgm-5519
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1218100; Gene model (P.falciparum): PF3D7_0320400; Gene product: oocyst capsule protein Cap380, putative
    Name tag: GFP-Strep
    Phenotype Oocyst;

  62. RMgm-5520
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1218100; Gene model (P.falciparum): PF3D7_0320400; Gene product: oocyst capsule protein Cap380, putative
    Name tag: GFP-Strep
    TaggedGene model (rodent): PBANKA_1202000; Gene model (P.falciparum): PF3D7_1003600; Gene product: inner membrane complex protein 1c, putative (IMC1c; ALV2)
    Name tag: mCherry
    Phenotype Oocyst;

  63. RMgm-5521
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_1430900; Gene model (P.falciparum): PF3D7_1215100; Gene product: SUN domain-containing protein, putative (SUN1)
    Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

  64. RMgm-5522
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1430900; Gene model (P.falciparum): PF3D7_1215100; Gene product: SUN domain-containing protein, putative (SUN1)
    Name tag: HA
    Phenotype Asexual bloodstage; Gametocyte/Gamete;

  65. RMgm-5523
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1304400; Gene model (P.falciparum): PF3D7_1440500; Gene product: allantoicase, putative (ALLC1)
    Name tag: HA
    Phenotype Gametocyte/Gamete;

  66. RMgm-5524
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_1019700; Gene model (P.falciparum): PF3D7_1423700; Gene product: NTF2-like domain-containing protein, putative (nuclear transport factor 2-like domain-containing protein)
    Phenotype Gametocyte/Gamete;

  67. RMgm-5525
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1019700; Gene model (P.falciparum): PF3D7_1423700; Gene product: NTF2-like domain-containing protein, putative (nuclear transport factor 2-like domain-containing protein)
    Name tag: mCherry
    Phenotype Asexual bloodstage; Gametocyte/Gamete;

  68. RMgm-5526
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_0519900; Gene model (P.falciparum): PF3D7_1036900; Gene product: conserved Plasmodium protein, unknown function
    Phenotype Asexual bloodstage;

  69. RMgm-5527
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_0519900; Gene model (P.falciparum): PF3D7_1036900; Gene product: conserved Plasmodium protein, unknown function
    Name tag: GFP
    Phenotype Asexual bloodstage;

  70. RMgm-5528
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_1117100; Gene model (P.falciparum): PF3D7_0617900; Gene product: histone H3 variant (H3.3)
    Transgene
    		 Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
    Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
    3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
    Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein
    Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

  71. RMgm-5529
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_1117100; Gene model (P.falciparum): PF3D7_0617900; Gene product: histone H3 variant (H3.3)
    Transgene
    		 Transgene not Plasmodium: RFP
    Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2)
    3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45)
    Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Transgene
    		 Transgene not Plasmodium: GFP (gfp-mut3)
    Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative
    3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam)
    Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p; 230p)
    Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

  72. RMgm-5530
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1117100; Gene model (P.falciparum): PF3D7_0617900; Gene product: histone H3 variant (H3.3)
    Name tag: HA
    Transgene
    		 Transgene not Plasmodium: RFP
    Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2)
    3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45)
    Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Transgene
    		 Transgene not Plasmodium: GFP (gfp-mut3)
    Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative
    3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam)
    Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p; 230p)
    Phenotype Asexual bloodstage; Gametocyte/Gamete; Sporozoite;

  73. RMgm-5531
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_1003300; Gene model (P.falciparum): PF3D7_0405600; Gene product: TMEM33 domain-containing protein, putative (TMEM33)
    Transgene
    		 Transgene not Plasmodium: eGFP
    Promoter: Gene model: Not available; Gene model (P.falciparum): Not available; Gene product: Not available
    3'UTR: Gene model: Not available; Gene product: Not available
    Replacement locus: Gene model: PBANKA_1003300; Gene product: TMEM33 domain-containing protein, putative (TMEM33)
    Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

  74. RMgm-5532
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1003300; Gene model (P.falciparum): PF3D7_0405600; Gene product: TMEM33 domain-containing protein, putative (TMEM33)
    Name tag: mNeon-Green (containing a twin-strep epitope)
    Phenotype Asexual bloodstage; Sporozoite;

  75. RMgm-5533
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1443000; Gene model (P.falciparum): PF3D7_1228300; Gene product: NIMA related kinase 1 (NEK1)
    Name tag: GFP
    Phenotype Asexual bloodstage; Gametocyte/Gamete; Oocyst; Liver stage;

  76. RMgm-5534
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1443000; Gene model (P.falciparum): PF3D7_1228300; Gene product: NIMA related kinase 1 (NEK1)
    Name tag: triple-HA
    Phenotype Gametocyte/Gamete;

  77. RMgm-5535
    Malaria parasiteP. berghei
    Genotype
    MutatedGene model (rodent): PBANKA_1443000; Gene model (P.falciparum): PF3D7_1228300; Gene product: NIMA related kinase 1 (NEK1)
    Details mutation: 'promoter swap mutant': the promoter of nek1 replaced with the clag2 promoter (PBANKA_1400600).
    Transgene
    		 Transgene not Plasmodium: GFP (gfp-mu3)
    Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
    3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
    Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

  78. RMgm-5536
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PBANKA_1217700; Gene model (P.falciparum): PF3D7_0320800; Gene product: ATP-dependent RNA helicase DDX6 (DOZI, protein development of zygote inhibited)
    Name tag: TurboID::GFP
    Phenotype Gametocyte/Gamete; Fertilization and ookinete;

  79. RMgm-5537
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1366000; Gene model (P.falciparum): PF3D7_1347500; Gene product: DNA/RNA-binding protein Alba 4 (ALBA4)
    Name tag: TurboID::GFP
    Phenotype Gametocyte/Gamete; Fertilization and ookinete;

  80. RMgm-5538
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0907300; Gene model (P.falciparum): PF3D7_1143100; Gene product: AP2 domain transcription factor AP2-O, putative (ApiAP2; AP2-O)
    Name tag: GFPmut2
    Phenotype Fertilization and ookinete;

  81. RMgm-5539
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_0417900; Gene model (P.falciparum): PF3D7_0903500; Gene product: nucleoporin NUP138, putative
    Name tag: spagheti monster Hemagglutinin' (smHA)
    Phenotype Asexual bloodstage;

  82. RMgm-5540
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1310200; Gene model (P.falciparum): PF3D7_1446500; Gene product: nucleoporin NUP313, putative
    Name tag: spagheti monster Hemagglutinin' (smHA)
    Phenotype Asexual bloodstage;

  83. RMgm-5541
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_0416300; Gene model (P.falciparum): PF3D7_0905100; Gene product: nucleoporin NUP221, putative (nucleoporin NUP100)
    Name tag: 3xHA/GFP
    Phenotype Asexual bloodstage;

  84. RMgm-5542
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP)
    Name tag: GFP
    Transgene
    		 Transgene Plasmodium: Gene model: PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP)
    Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 | protein of early gametocyte 4 (UIS4; ETRAMP10.3)
    3'UTR: Gene model: PBANKA_0403200; Gene product: circumsporozoite (CS) protein (CSP)
    Insertion locus: Gene model: Not available; Gene product: Not available
    Phenotype Sporozoite;

  85. RMgm-5543
    Malaria parasiteP. yoelii
    Genotype
    Genetic modification not successful
    DisruptedGene model (rodent): PY17X_0210200; Gene model (P.falciparum): PF3D7_0104300; Gene product: ubiquitin carboxyl-terminal hydrolase 1, putative (UBP1)
    PhenotypeNo phenotype has been described
  86. RMgm-5544
    Malaria parasiteP. yoelii
    Genotype
    MutatedGene model (rodent): PY17X_0210200; Gene model (P.falciparum): PF3D7_0104300; Gene product: ubiquitin carboxyl-terminal hydrolase 1, putative (UBP1)
    Details mutation: UBP1 mutated - two mutated amino acids (I1560N and P2874T)
    Phenotype Asexual bloodstage;

  87. RMgm-5545
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_0210200; Gene model (P.falciparum): PF3D7_0104300; Gene product: ubiquitin carboxyl-terminal hydrolase 1, putative (UBP1)
    Name tag: 6x-HA
    Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

  88. RMgm-5546
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1241000; Gene model (P.falciparum): PF3D7_0523000; Gene product: multidrug resistance protein 1 | ABC transporter B family member 1 (MDR1; ABCB1; Pgh1)
    Name tag: 4x-Myc
    Phenotype Asexual bloodstage;

  89. RMgm-5547
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1241000; Gene model (P.falciparum): PF3D7_0523000; Gene product: multidrug resistance protein 1 | ABC transporter B family member 1 (MDR1; ABCB1; Pgh1)
    Name tag: 4x-Myc
    TaggedGene model (rodent): PY17X_0210200; Gene model (P.falciparum): PF3D7_0104300; Gene product: ubiquitin carboxyl-terminal hydrolase 1, putative (UBP1)
    Name tag: 6x-HA
    Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

  90. RMgm-5548
    Malaria parasiteP. yoelii
    Genotype
    TaggedGene model (rodent): PY17X_1241000; Gene model (P.falciparum): PF3D7_0523000; Gene product: multidrug resistance protein 1 | ABC transporter B family member 1 (MDR1; ABCB1; Pgh1)
    Name tag: mCherry
    Phenotype Asexual bloodstage;

  91. RMgm-5549
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_1411400; Gene model (P.falciparum): PF3D7_1313000; Gene product: Ubiquitin-like protein nedd8 homologue, putative (NEDD8)
    Transgene
    		 Transgene not Plasmodium: GFP
    Promoter: Gene model: Not available; Gene model (P.falciparum): Not available; Gene product: Not available
    3'UTR: Gene model: Not available; Gene product: Not available
    Replacement locus: Gene model: PBANKA_1411400; Gene product: Ubiquitin-like protein nedd8 homologue, putative (NEDD8)
    Phenotype Fertilization and ookinete; Oocyst; Sporozoite;

  92. RMgm-5550
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_1110700; Gene model (P.falciparum): PF3D7_0511200; Gene product: Stearoyl-CoA desaturase (Scd)
    Transgene
    		 Transgene not Plasmodium: GFP
    Promoter: Gene model: Not available; Gene model (P.falciparum): Not available; Gene product: Not available
    3'UTR: Gene model: Not available; Gene product: Not available
    Insertion locus: Gene model: PBANKA_1110700; Gene product: Stearoyl-CoA desaturase (Scd)
    Phenotype Liver stage;

  93. RMgm-5551
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1110700; Gene model (P.falciparum): PF3D7_0511200; Gene product: Stearoyl-CoA desaturase (Scd)
    Name tag: triple-HA
    Phenotype Asexual bloodstage; Liver stage;

  94. RMgm-5552
    Malaria parasiteP. berghei
    Genotype
    DisruptedGene model (rodent): PBANKA_0810400; Gene model (P.falciparum): PF3D7_0909200; Gene product: GDP-fucose protein O-fucosyltransferase 2 (O‑Fucosyltransferase; POFut2)
    Transgene
    		 Transgene not Plasmodium: GFP
    Promoter: Gene model: Not available; Gene model (P.falciparum): Not available; Gene product: Not available
    3'UTR: Gene model: Not available; Gene product: Not available
    Insertion locus: Gene model: PBANKA_1110700; Gene product: Stearoyl-CoA desaturase (Scd)
    Phenotype Sporozoite; Liver stage;

  95. RMgm-5553
    Malaria parasiteP. yoelii
    Genotype
    DisruptedGene model (rodent): PY17X_1123700; Gene model (P.falciparum): PF3D7_0623400; Gene product: MEI2-like RNA-binding protein, putative (PlasMei2)
    DisruptedGene model (rodent): PY17X_1465200; Gene model (P.falciparum): PF3D7_1249700; Gene product: conserved Plasmodium protein, unknown function (LINUP, liver stage nuclear protein)
    Phenotype Liver stage;

  96. RMgm-5554
    Malaria parasiteP. yoelii
    Genotype
    Genetic modification not successful
    DisruptedGene model (rodent): PYYM_1014900; Gene model (P.falciparum): PF3D7_1431400; Gene product: Surface-related antigen SRA (SRA)
    PhenotypeNo phenotype has been described
  97. RMgm-5555
    Malaria parasiteP. berghei
    Genotype
    Transgene
    		 Transgene not Plasmodium: CAS9 (tagged with FLAG)
    Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
    3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70)
    Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
    Phenotype Asexual bloodstage;

  98. RMgm-5556
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1101400; Gene model (P.falciparum): PF3D7_0501600; Gene product: rhoptry-associated protein 2 (RAP2/3; rhoptry-associated protein 2/3)
    Name tag: triple-HA
    Phenotype Asexual bloodstage;

  99. RMgm-5557
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1224200; Gene model (P.falciparum): PF3D7_0806500; Gene product: DnaJ protein, putative
    Name tag: 3xcMyc
    Phenotype Asexual bloodstage;

  100. RMgm-5558
    Malaria parasiteP. berghei
    Genotype
    TaggedGene model (rodent): PBANKA_1225600; Gene model (P.falciparum): PF3D7_0805000; Gene product: alpha/beta hydrolase, putative
    Name tag: 3xcMyc
    Phenotype Asexual bloodstage;

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P.berghei model of malaria
Technical design and realization: S. Mededovic and A. van Wigcheren