Search database by RMgm ID
RMgm-396
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PBANKA_0813000; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (inhibitor of cysteine proteases; ICP) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-844
Malaria parasite | P. yoelii |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PY17X_0816300; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (ICP; falstatin) |
Phenotype | No phenotype has been described |
RMgm-845
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_0816300; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (ICP; falstatin) Name tag: c-myc |
Phenotype |
Asexual bloodstage;
Sporozoite; Liver stage; |
RMgm-850
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_0816300; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (ICP; falstatin) Name tag: RFA tag with an HA epitope and an E. coli DHFR degradation domain (DDD) |
Phenotype |
Asexual bloodstage;
|
RMgm-970
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0813000; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (falstatin; PbICP; ICP) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1113
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0813000; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (falstatin; PbICP; ICP) Details mutation: The mutant contains a FRTed ORF of the icp locus Details conditional mutagenesis: The ORF of icp is removed in the sporozoite stage by the Flp/FRT system. |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1114
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0813000; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (falstatin; PbICP; ICP) |
Phenotype |
Asexual bloodstage;
Sporozoite; Liver stage; |
RMgm-1313
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_0911900; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (ICP) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1483
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0813000; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (ICP) Name tag: GFP |
Phenotype |
Gametocyte/Gamete;
|
RMgm-4226
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0813000; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases |
Phenotype | No phenotype has been described |